1H-Isoindole-1,3(2H)-dione, 4-[(4-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-
4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
CAS: 1957236-34-8
Molecular Formula: C17H20N4O4
1H-Isoindole-1,3(2H)-dione, 4-[(4-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)- - Names and Identifiers
1H-Isoindole-1,3(2H)-dione, 4-[(4-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)- - Physico-chemical Properties
| Molecular Formula | C17H20N4O4 |
| Molar Mass | 344.37 |
1H-Isoindole-1,3(2H)-dione, 4-[(4-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)- - Introduction
4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is a semi-synthetic organic compound. The following is a description of its properties, uses, preparation methods and safety information:
Nature:
-Appearance: The compound was a white crystalline solid.
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dimethylformamide, insoluble in water.
Use:
-Drug research: Due to its isoindole skeleton and dione functional group, this compound is often used as an intermediate or raw material for drug research. It has potential anti-tumor, anti-inflammatory and anti-microbial activities, so it has a wide range of applications in the field of anti-cancer agents and drug discovery.
Preparation Method:
4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1, the preparation method of 3-dione is generally synthesized step by step by chemical reaction. The specific synthesis steps may vary depending on the purpose of the study, but the following is a possible synthesis method:
1.2-fluoro -1,3-dione isoindole is substituted with p-aminobutanol to obtain 4-((4-aminobutyl) amino)-2-hydrogen -1,3-dione isoindole.
2. the product obtained in step 1 and 2,6-dioxo-piperidin-3-one undergo a thionyl chloride-catalyzed condensation reaction to generate 4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione.
3. Pure products are obtained by methods such as crystallization.
Safety Information:
Information on the exact toxicity and safety of 4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione may be limited, so it is necessary to follow laboratory safety procedures when handling and using. Appropriate precautions should be taken, including gloves, goggles and outside laboratory operations. During handling and storage, keep away from ignition and oxidizing agents and keep them properly to prevent accidental leakage. It is recommended to operate in a specialized laboratory environment and follow relevant regulations and guidelines. Appropriate risk assessments should also be made and safety practices observed when using the compound.
Nature:
-Appearance: The compound was a white crystalline solid.
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dimethylformamide, insoluble in water.
Use:
-Drug research: Due to its isoindole skeleton and dione functional group, this compound is often used as an intermediate or raw material for drug research. It has potential anti-tumor, anti-inflammatory and anti-microbial activities, so it has a wide range of applications in the field of anti-cancer agents and drug discovery.
Preparation Method:
4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1, the preparation method of 3-dione is generally synthesized step by step by chemical reaction. The specific synthesis steps may vary depending on the purpose of the study, but the following is a possible synthesis method:
1.2-fluoro -1,3-dione isoindole is substituted with p-aminobutanol to obtain 4-((4-aminobutyl) amino)-2-hydrogen -1,3-dione isoindole.
2. the product obtained in step 1 and 2,6-dioxo-piperidin-3-one undergo a thionyl chloride-catalyzed condensation reaction to generate 4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione.
3. Pure products are obtained by methods such as crystallization.
Safety Information:
Information on the exact toxicity and safety of 4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione may be limited, so it is necessary to follow laboratory safety procedures when handling and using. Appropriate precautions should be taken, including gloves, goggles and outside laboratory operations. During handling and storage, keep away from ignition and oxidizing agents and keep them properly to prevent accidental leakage. It is recommended to operate in a specialized laboratory environment and follow relevant regulations and guidelines. Appropriate risk assessments should also be made and safety practices observed when using the compound.
Last Update：2024-04-09 21:54:55
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